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1.
Rev. méd. Chile ; 127(11): 1369-74, nov. 1999. ilus, tab
Article in Spanish | LILACS | ID: lil-257997

ABSTRACT

We report a 24 years old female with a superior mesenteric and portal vein thrombosis due to an antithrombin III factor deficiency, associated to oral contraceptive use and smoking. She presented with severe abdominal pain and the diagnosis was reached after surgery with a CT scan. The patient was treated with intravenous heparin and oral anticoagulation, with a good clinical and doppler endosonographic response. One month after the onset, she developed an intestinal occlusion caused by two concentric jejunal stenoses, measuring 2 and 0.7 cm in length and demonstrated with a barium jejunogram. A 35 cm intestinal resection was done and the patient recovered uneventfully. The pathological study showed granulation tissue on both stenotic zones with an ulcer near to the distal stricture, that reached the internal muscularis propria, with subserosal fibrosis. The development of segmental stenosis is a rare complication superior mesenteric vein thrombosis, that must be bore in mind


Subject(s)
Humans , Female , Adult , Thrombosis , Intestinal Obstruction/etiology , Mesenteric Vascular Occlusion/complications , Portal Vein , Antithrombin III Deficiency , Anticoagulants/therapeutic use , Intestinal Obstruction/surgery , Intestinal Obstruction/diagnosis , Mesenteric Vascular Occlusion/diagnosis , Mesenteric Vascular Occlusion/etiology , Mesenteric Veins
2.
Rev. chil. enferm. respir ; 10(1): 45-53, ene.-mar. 1994. ilus
Article in Spanish | LILACS | ID: lil-194561

ABSTRACT

La amiodarona es una potente droga antiarrítmica de importante uso en nuestro medio, caracterizada por su prolongada vida media de eliminación. Se le ha descrito una reacción adversa pulmonar que se manifiesta como una enfermedad difusa, intersticial y/o alveolar, con una incidencia promedio de 5 a 7 por ciento de los casos. Esta alveolitis presenta una importante complejidad diagnóstica, tanto por la multiplicidad de diagnósticos diferenciales, como por la ausencia de una prueba específica y precoz. Se presentan dos casos de alveolitis por amiodarona cuyo diagnóstico y seguimiento se realizó con la prueba de Tc99m-DTPA. Esta prueba resultó significativamente disminuida (menos del 50 por ciento del valor normal) en el momento del diagnóstico y se mantuvo anormalmente baja por tiempo prolongado a pesar del tratamiento esteroidal. Se discuten algunos aspectos de esta prueba radioisotópica y sus alcances diagnósticos y de seguimiento en el daño pulmonar unducido por amiodarona


Subject(s)
Humans , Male , Aged , Amiodarone/adverse effects , Blood-Air Barrier/physiology , Lung Diseases, Interstitial/chemically induced , Capillary Permeability/physiology , Lung Diseases, Interstitial , Technetium Tc 99m Pentetate
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